This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 642157


Italy bandiera 72 University of Milano Bicocca
Spain 72 Agencia Estatal Consejo Superior de Invest. Cientificas
Germany 72 University of Bielefeld
Spain 72 Asoc. Centro de Invest. Coop. en Biomateriales – CIC
Spain 72 Diomune SL
slovenia 72 Kemijski Institut
Spain 72 Asoc. Centro de Invest. Coop. en Biociencias – CIC
Belgium 72 VIB
Italy bandiera 72 Lofarma SpA
Italy bandiera 72 Università degli Studi di Napoli Federico II

Partner Organizations

USA 72 Massachusetts Institute of Technology
Italy bandiera 72 University of Padova
Spain 72 Universidad Europea de Madrid

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TOLLerant Kick-off Meeting

kick-off TOLLerant Gang Feb 2015

11-12 February 2015, University of Milano Bicocca, Milan, Italy

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TOLLerant 2nd MEETING – Madrid 2016

24 – 27 May, 2016. Madrid, Spain
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TOLLerant 3rd MEETING – Ljubljana 2016

14 – 16 December, 2016. Ljubljana, Slovenia
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TOLLerant 4th MEETING – Napoli 2017

5th to 7th June, 2017. Napoli, Italy
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TOLLerant 5th MEETING – Ghent 2017

12th to 15th December, 2017. Ghent, Belgium
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The Project – TOLLerant

Based on an international team derived from the COST action BM1003 (, 2011-2014) and thus relying on consolidated group interactions and synergies and on a unique combination of chemistry, biology, biophysics, biochemistry and pharmacology expertise, the TOLLerant project aims to gain information on molecular aspects of TLR4 activation and signalling by using synthetic and natural compounds and nanoparticles that interact selectively with some components (mainly MD-2 and CD14) of the TRL4 recognition system.
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  • MicrobiotaMi 2018

    5th - 7th November, 2018. Milan, Italy.
    The aim of this International meeting is to focus on the molecular mechanisms and interactions in health ...
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News Archive

Early Stage Researcher (ESR) Publications

Modulation of endothelial function by Toll like receptors.
Pharmacol Res. 2016, 108, 46-56; doi: 10.1016/j.phrs.2016.03.038
Salvador B, Arranz A, Francisco S, Córdoba L, Punzón C, Llamas MÁ, Fresno M.
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Computational Approaches to Toll-Like Receptor 4 Modulation.
Molecules 2016, 21(8), 994; doi:10.3390/molecules21080994
Billod JM, Lacetera A, Guzmán-Caldentey J, Martin-Santamaría S.
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Recent Publications

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