TOLLerant 4^th MEETING – Napoli 2017

5^th – 7^th June, 2017. Napoli, Italy

“Molecular Aspects of Host/Microbe dialogue”

Sponsored by IEIIS

Meeting Venue: Università di Napoli Federico II
“Complesso dei SS. Marcellino e Festo”
Address: Largo S. Marcellino, 10 – Napoli

Organizing Committee: Alba Silipo, Francesco Peri, Flaviana Di Lorenzo, Roberta Marchetti

Registration is CLOSED

Program

Monday June 5^th

17:00 – 20:00 Networking and social activity

20:00 Dinner

Tuesday June 6^th

09:00 – 9:15 Opening: Alba Silipo and Francesco Peri

“The molecular code of lectin/sugar interactions”

09:15 – 10:00 Cristina Nativi, University of Florence, Italy
Antigens Multivalent Presentation to Immunesystem

10:00 – 10:45 Niels-Christian Reichardt; CIC-biomaGUNE, Bilbao, Spain
Parasite Glycans as Lead Structures for Dendritic Cell Targeting.

10:45 – 11:15 Coffee Break

11:15 – 12:00 Javier Rojo, Spain
Glycodendritic systems to inhibit DC-SIGN-dependent pathogen-cell interactions

“The molecular code of TLR/ligands interactions”

12:00 – 12:45 Koichi Fukase, University of Osaka, Japan
Chemical synthesis of immunologically relevant prokaryotic and eukaryotic glycoconjugates

12:45 – 13:30 Grisha Pirianov, Anglia Ruskin Cambridge University, UK
A novel synthetic molecules negatively regulate in vitro and in vivo haematopoietic and non-haematopoietic vascular toll like receptor 4 signalling in response to sterile inflammation

13:30 – 14:45 Lunch

14:45 – 15:30 Francesco Peri, University of Milano-Bicocca
Recent achievements on the study of TLR4 modulation by natural and synthetic molecules: an update on TOLLerant network activity

15:30 – 16:15 Jerrold Weiss, University of Iowa (USA)
Novel insights and speculations concerning molecular requirements for MD-2/TLR4 activation and antagonism

16:15 – 16:45 Coffee Break

16:45 – 18:25 ESR presentations (Slideshow 10 minutes/ESR)

20:30 Dinner

Wednesday June 7^th

The molecular code of TLR/ligands interactions

09:00 – 09:45 M. L. Bernardini, University of Rome – La Sapienza
PAMPs and PRRs: the hide and seek of pathogens and the immune system

9:45 – 10:30 R. Jerala, University of Lujbljana, Slovenia
New mechanisms of regulation of MyD88-mediated signaling in innate immunity.

10:30 – 11:15 F. Di Lorenzo, University of Naples, Italy
Chemistry and Immunity of lipopolysaccharides

11:15 – 11:45 Coffee Break

11:45 – 12:30 Thomas Huser, University of Bielefield, Germany
Imaging live cell receptor dynamics with super-resolution fluorescence microscopy

12:30 – 13:15 Sonsoles Martin Santamaria, CIB-CSIC, Madrid, Spain
The Computational Perspective into the Host/Microbe Dialogue

13:15 – 13:45 ESR presentations (Slideshow 10 minutes/ESR)

13:45 – 14:00 Closing Remarks

14:00-15.00 Lunch