TOLLerant 4th MEETING – Napoli 2017

5th – 7th June, 2017. Napoli, Italy

“Molecular Aspects of Host/Microbe dialogue”

Sponsored by IEIIS

Meeting Venue: Università di Napoli Federico II
“Complesso dei SS. Marcellino e Festo”
Address: Largo S. Marcellino, 10 – Napoli

Organizing Committee: Alba Silipo, Francesco Peri, Flaviana Di Lorenzo, Roberta Marchetti

Registration is CLOSED

Program

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Monday June 5th

    17:00 – 20:00 Networking and social activity

    20:00 Dinner

Tuesday June 6th

    09:00 – 9:15 Opening: Alba Silipo and Francesco Peri

    “The molecular code of lectin/sugar interactions”

    09:15 – 10:00 Cristina Nativi, University of Florence, Italy
    Antigens Multivalent Presentation to Immunesystem

    10:00 – 10:45 Niels-Christian Reichardt; CIC-biomaGUNE, Bilbao, Spain
    Parasite Glycans as Lead Structures for Dendritic Cell Targeting.

    10:45 – 11:15 Coffee Break

    11:15 – 12:00 Javier Rojo, Spain
    Glycodendritic systems to inhibit DC-SIGN-dependent pathogen-cell interactions

    “The molecular code of TLR/ligands interactions”

    12:00 – 12:45 Koichi Fukase, University of Osaka, Japan
    Chemical synthesis of immunologically relevant prokaryotic and eukaryotic glycoconjugates

    12:45 – 13:30 Grisha Pirianov, Anglia Ruskin Cambridge University, UK
    A novel synthetic molecules negatively regulate in vitro and in vivo haematopoietic and non-haematopoietic vascular toll like receptor 4 signalling in response to sterile inflammation

    13:30 – 14:45 Lunch

    14:45 – 15:30 Francesco Peri, University of Milano-Bicocca
    Recent achievements on the study of TLR4 modulation by natural and synthetic molecules: an update on TOLLerant network activity

    15:30 – 16:15 Jerrold Weiss, University of Iowa (USA)
    Novel insights and speculations concerning molecular requirements for MD-2/TLR4 activation and antagonism

    16:15 – 16:45 Coffee Break

    16:45 – 18:25 ESR presentations (Slideshow 10 minutes/ESR)

    20:30 Dinner

Wednesday June 7th

    The molecular code of TLR/ligands interactions

    09:00 – 09:45 M. L. Bernardini, University of Rome – La Sapienza
    PAMPs and PRRs: the hide and seek of pathogens and the immune system

    9:45 – 10:30 R. Jerala, University of Lujbljana, Slovenia
    New mechanisms of regulation of MyD88-mediated signaling in innate immunity.

    10:30 – 11:15 F. Di Lorenzo, University of Naples, Italy
    Chemistry and Immunity of lipopolysaccharides

    11:15 – 11:45 Coffee Break

    11:45 – 12:30 Thomas Huser, University of Bielefield, Germany
    Imaging live cell receptor dynamics with super-resolution fluorescence microscopy

    12:30 – 13:15 Sonsoles Martin Santamaria, CIB-CSIC, Madrid, Spain
    The Computational Perspective into the Host/Microbe Dialogue

    13:15 – 13:45 ESR presentations (Slideshow 10 minutes/ESR)

    13:45 – 14:00 Closing Remarks

    14:00-15.00 Lunch