EGFR(B1D8) , CF405S conjugate , 0.1mg / mL

This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1 , -2 , -3 -4 or HER-1 , -2 , -3 -4. It binds to Epidermal Growth Factor (EGF) , Transforming Growth Factor-a (TGF-a) , Heparin-binding EGF (HB-EGF) , amphiregulin , βcellulin and epiregulin.Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.