Volume : 50 µg
Clone Number :
Aliases : ASL13 antibody; Ataxin 2 antibody; Ataxin-2 antibody; ATX2_HUMAN antibody; Atxn2 antibody; Olivopontocerebellar ataxia 2; autosomal dominant antibody; SCA2 antibody; Spinocerebellar ataxia type 2 protein antibody; TNRC13 antibody; Trinucleotide repeat containing 13 antibody; Trinucleotide repeat containing gene 13 protein antibody; Trinucleotide repeat-containing gene 13 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99700
Immunogen : Recombinant Human Ataxin-2 protein (174-383AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in EGFR trafficking, acting as negative reg µLator of endocytic EGFR internalization at the plasma membrane.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cell biology

Volume : 50 µg
Clone Number :
Aliases : ASL13 antibody; Ataxin 2 antibody; Ataxin-2 antibody; ATX2_HUMAN antibody; Atxn2 antibody; Olivopontocerebellar ataxia 2; autosomal dominant antibody; SCA2 antibody; Spinocerebellar ataxia type 2 protein antibody; TNRC13 antibody; Trinucleotide repeat containing 13 antibody; Trinucleotide repeat containing gene 13 protein antibody; Trinucleotide repeat-containing gene 13 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99700
Immunogen : Recombinant Human Ataxin-2 protein (174-383AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in EGFR trafficking, acting as negative reg µLator of endocytic EGFR internalization at the plasma membrane.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cell biology

Volume : 50 µg
Clone Number :
Aliases : ASL13 antibody; Ataxin 2 antibody; Ataxin-2 antibody; ATX2_HUMAN antibody; Atxn2 antibody; Olivopontocerebellar ataxia 2; autosomal dominant antibody; SCA2 antibody; Spinocerebellar ataxia type 2 protein antibody; TNRC13 antibody; Trinucleotide repeat containing 13 antibody; Trinucleotide repeat containing gene 13 protein antibody; Trinucleotide repeat-containing gene 13 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99700
Immunogen : Recombinant Human Ataxin-2 protein (174-383AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in EGFR trafficking, acting as negative reg µLator of endocytic EGFR internalization at the plasma membrane.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cell biology

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ATXN2
GeneID : 6311
Uniprot : Q99700
Specificity : ATXN2 Antibody detects endogenous levels of total ATXN2.
Immunogen : A syntheVolumed peptide derived from human ATXN2, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2836156
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3799-BP
Des# Blocking Peptide : ATXN2 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : ATXN1L antibody; BOAT antibody; BOAT1Ataxin-1-like antibody; Brother of ataxin-1 antibody; Brother of ATXN1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P0C7T5
Immunogen : Recombinant Human Ataxin-1-like protein (183-463AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Chromatin-binding factor that repress Notch signaling in the absence of Notch intracell µLar domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1) (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN1L
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : ATXN1L antibody; BOAT antibody; BOAT1Ataxin-1-like antibody; Brother of ataxin-1 antibody; Brother of ATXN1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P0C7T5
Immunogen : Recombinant Human Ataxin-1-like protein (183-463AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Chromatin-binding factor that repress Notch signaling in the absence of Notch intracell µLar domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1) (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN1L
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : ATXN1L antibody; BOAT antibody; BOAT1Ataxin-1-like antibody; Brother of ataxin-1 antibody; Brother of ATXN1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P0C7T5
Immunogen : Recombinant Human Ataxin-1-like protein (183-463AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Chromatin-binding factor that repress Notch signaling in the absence of Notch intracell µLar domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1) (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN1L
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : ATXN1L antibody; BOAT antibody; BOAT1Ataxin-1-like antibody; Brother of ataxin-1 antibody; Brother of ATXN1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P0C7T5
Immunogen : Recombinant Human Ataxin-1-like protein (183-463AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC; Recommended dilution : IHC : 1 : 20-1 : 200
Background : Chromatin-binding factor that repress Notch signaling in the absence of Notch intracell µLar domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1) (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN1L
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ATXN10
GeneID : 25814
Uniprot : Q9UBB4
Specificity : ATXN10 Antibody detects endogenous levels of total ATXN10.
Immunogen : A syntheVolumed peptide derived from human ATXN10, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Rabbit,Dog
Application : WB,ELISA(peptide)
Dilution : WB 1 : 1000-3000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842427
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF9231-BP
Des# Blocking Peptide : ATXN10 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : alternative ataxin1 antibody; Ataxin-1 antibody; ATX1 antibody; ATX1_HUMAN antibody; Atxn1 antibody; D6S504E antibody; OTTHUMP00000016065 antibody; SCA1 antibody; Spinocerebellar ataxia type 1 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P54253
Immunogen : SyntheVolumed peptide derived from Human Ataxin-1 around the non-phosphorylation site of S776.
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : WB, IHC, IF, ELISA; IHC : 1 : 100-1 : 300, IF : 1 : 200-1 : 1000, ELISA : 1 : 5000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN1
Research Areas : Epigenetics and Nuclear Signaling?Neuroscience

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : ATXN3, which has deubiquitinase activity and act as a component of the ubiquitin proteasome system, plays a role in transcriptional reg µLation and neuroprotection. ATXN3 interacts with RAD23, HHR23A and HHR23B, involves in the pathology of MJD. ATXN3 is a mixed-linkage, chain-editing enzyme and that the UIM region of ATXN3 reg µLates its substrate specificity. Contains an N-terminal deubiquitinating domain, called the Josephin domain, followed by 2 ubiquitin-interacting motifs (UIMs) and a polyQ tract near the C terminus. ATXN3 can be phosphorylated in a protein casein kinase-2-dependent manner, thus the MW wo µLd be larger than the predicted one.
Immunogen : ataxin 3
Aliases : AT3, ataxin 3, ATX3, ATXN3, JOS, MJD, MJD1 SCA3
Observed MW : 38 kDa
Uniprot ID : P54252
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500-1 : 1000; IHC : 1 : 20-1 : 200
Gene ID :
Research Area : Neuroscience, Metabolism, Developmental biology

Volume : 50 µg
Clone Number :
Aliases : Alpha thalassemia/mental retardation syndrome X linked homolog antibody; ATP dependent helicase ATRX antibody; ATP-dependent helicase ATRX antibody; ATR2 antibody; Atrx antibody; ATRX_HUMAN antibody; DNA dependent ATPase and helicase antibody; Helicase 2; X linked antibody; MGC2094 antibody; MRXHF1 antibody; RAD54 antibody; RAD54L antibody; SFM1 antibody; SHS antibody; Transcriptional reg µLator ATRX antibody; X linked helicase II antibody; X linked nuclear protein antibody; X-linked helicase II antibody; X-linked nuclear protein antibody; XH2 antibody; XNP antibody; Znf HX antibody; Znf-HX antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P46100
Immunogen : Recombinant Human Transcriptional reg µLator ATRX protein (2161-2443AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in transcriptional reg µLation and chromatin remodeling. Facilitates DNA replication in m µLtiple cell µLar environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into reg µLar chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX : DAXX which has ATP-dependent DNA translocase activity and catalyzes the replication-independent deposition of histone H3.3 in pericentric DNA repeats outside S-phase and telomeres, and the in vitro remodeling of H3.3-containing nucleosomes. Its heterochromatin targeting is proposed to involve a combinatorial readout of histone H3 modifications (specifically methylation states of H3K9 and H3K4) and association with CBX5. Involved in maintaining telomere structural integrity in embryonic stem cells which probably implies recruitment of CBX5 to telomers. Reports on the involvement in transcriptional reg µLation of telomeric repeat-containing RNA (TERRA) are conflicting; according to a report, it is not sufficient to decrease chromatin condensation at telomers nor to increase expression of telomeric RNA in fibroblasts (PubMed : 24500201). May be involved in telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines. Acts as negative reg µLator of chromatin incorporation of transcriptionally repressive histone H2AFY, partic µLarily at telomeres and the alpha-globin cluster in erythroleukemic cells. Participates in the allele-specific gene expression at the imprinted IGF2/H19 gene locus. On the maternal allele, required for the chromatin occupancy of SMC1 and CTCTF within the H19 imprinting control region (ICR) and involved in esatblishment of histone tails modifications in the ICR. May be involved in brain development and facial morphogenesis. Binds to zinc-finger coding genes with atypical chromatin signatures and reg µLates its H3K9me3 levels. Forms a complex with ZNF274, TRIM28 and SETDB1 to facilitate the deposition and maintenance of H3K9me3 at the 3\' exons of zinc-finger genes (PubMed : 27029610).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATRX
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Alpha thalassemia/mental retardation syndrome X linked homolog antibody; ATP dependent helicase ATRX antibody; ATP-dependent helicase ATRX antibody; ATR2 antibody; Atrx antibody; ATRX_HUMAN antibody; DNA dependent ATPase and helicase antibody; Helicase 2; X linked antibody; MGC2094 antibody; MRXHF1 antibody; RAD54 antibody; RAD54L antibody; SFM1 antibody; SHS antibody; Transcriptional reg µLator ATRX antibody; X linked helicase II antibody; X linked nuclear protein antibody; X-linked helicase II antibody; X-linked nuclear protein antibody; XH2 antibody; XNP antibody; Znf HX antibody; Znf-HX antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P46100
Immunogen : Recombinant Human Transcriptional reg µLator ATRX protein (2161-2443AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in transcriptional reg µLation and chromatin remodeling. Facilitates DNA replication in m µLtiple cell µLar environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into reg µLar chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX : DAXX which has ATP-dependent DNA translocase activity and catalyzes the replication-independent deposition of histone H3.3 in pericentric DNA repeats outside S-phase and telomeres, and the in vitro remodeling of H3.3-containing nucleosomes. Its heterochromatin targeting is proposed to involve a combinatorial readout of histone H3 modifications (specifically methylation states of H3K9 and H3K4) and association with CBX5. Involved in maintaining telomere structural integrity in embryonic stem cells which probably implies recruitment of CBX5 to telomers. Reports on the involvement in transcriptional reg µLation of telomeric repeat-containing RNA (TERRA) are conflicting; according to a report, it is not sufficient to decrease chromatin condensation at telomers nor to increase expression of telomeric RNA in fibroblasts (PubMed : 24500201). May be involved in telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines. Acts as negative reg µLator of chromatin incorporation of transcriptionally repressive histone H2AFY, partic µLarily at telomeres and the alpha-globin cluster in erythroleukemic cells. Participates in the allele-specific gene expression at the imprinted IGF2/H19 gene locus. On the maternal allele, required for the chromatin occupancy of SMC1 and CTCTF within the H19 imprinting control region (ICR) and involved in esatblishment of histone tails modifications in the ICR. May be involved in brain development and facial morphogenesis. Binds to zinc-finger coding genes with atypical chromatin signatures and reg µLates its H3K9me3 levels. Forms a complex with ZNF274, TRIM28 and SETDB1 to facilitate the deposition and maintenance of H3K9me3 at the 3\' exons of zinc-finger genes (PubMed : 27029610).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATRX
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Alpha thalassemia/mental retardation syndrome X linked homolog antibody; ATP dependent helicase ATRX antibody; ATP-dependent helicase ATRX antibody; ATR2 antibody; Atrx antibody; ATRX_HUMAN antibody; DNA dependent ATPase and helicase antibody; Helicase 2; X linked antibody; MGC2094 antibody; MRXHF1 antibody; RAD54 antibody; RAD54L antibody; SFM1 antibody; SHS antibody; Transcriptional reg µLator ATRX antibody; X linked helicase II antibody; X linked nuclear protein antibody; X-linked helicase II antibody; X-linked nuclear protein antibody; XH2 antibody; XNP antibody; Znf HX antibody; Znf-HX antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P46100
Immunogen : Recombinant Human Transcriptional reg µLator ATRX protein (2161-2443AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in transcriptional reg µLation and chromatin remodeling. Facilitates DNA replication in m µLtiple cell µLar environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into reg µLar chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX : DAXX which has ATP-dependent DNA translocase activity and catalyzes the replication-independent deposition of histone H3.3 in pericentric DNA repeats outside S-phase and telomeres, and the in vitro remodeling of H3.3-containing nucleosomes. Its heterochromatin targeting is proposed to involve a combinatorial readout of histone H3 modifications (specifically methylation states of H3K9 and H3K4) and association with CBX5. Involved in maintaining telomere structural integrity in embryonic stem cells which probably implies recruitment of CBX5 to telomers. Reports on the involvement in transcriptional reg µLation of telomeric repeat-containing RNA (TERRA) are conflicting; according to a report, it is not sufficient to decrease chromatin condensation at telomers nor to increase expression of telomeric RNA in fibroblasts (PubMed : 24500201). May be involved in telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines. Acts as negative reg µLator of chromatin incorporation of transcriptionally repressive histone H2AFY, partic µLarily at telomeres and the alpha-globin cluster in erythroleukemic cells. Participates in the allele-specific gene expression at the imprinted IGF2/H19 gene locus. On the maternal allele, required for the chromatin occupancy of SMC1 and CTCTF within the H19 imprinting control region (ICR) and involved in esatblishment of histone tails modifications in the ICR. May be involved in brain development and facial morphogenesis. Binds to zinc-finger coding genes with atypical chromatin signatures and reg µLates its H3K9me3 levels. Forms a complex with ZNF274, TRIM28 and SETDB1 to facilitate the deposition and maintenance of H3K9me3 at the 3\' exons of zinc-finger genes (PubMed : 27029610).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATRX
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ATRX
GeneID : 546
Uniprot : P46100
Specificity : ATRX Antibody detects endogenous levels of total ATRX.
Immunogen : A syntheVolumed peptide derived from human ATRX, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Bovine,Rabbit,Dog
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : IF/ICC 1 : 100-1 : 500, WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2834239
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF0413-BP
Des# Blocking Peptide : ATRX Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ATN1
GeneID : 1822
Uniprot : P54259
Specificity : Atrophin 1 Antibody detects endogenous levels of total Atrophin 1.
Immunogen : A syntheVolumed peptide derived from human Atrophin 1 corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2836181
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3824-BP
Des# Blocking Peptide : Atrophin 1 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ATRNL1
GeneID : 26033
Uniprot : Q5VV63
Specificity : ATRNL1 Antibody detects endogenous levels of ATRNL1.
Immunogen : A syntheVolumed peptide derived from human ATRNL1.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF15182-BP
Des# Blocking Peptide : ATRNL1 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ATRN
GeneID : 8455
Uniprot : O75882
Specificity : ATRN Antibody detects endogenous levels of total ATRN.
Immunogen : A syntheVolumed peptide derived from human ATRN, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reactivity : Human
Prediction : Pig,Bovine,Rabbit,Dog
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839838
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF2632-BP
Des# Blocking Peptide : ATRN Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : ATRIP
GeneID : 84126
Uniprot : Q8WXE1
Specificity : ATRIP Antibody detects endogenous levels of total ATRIP.
Immunogen : A syntheVolumed peptide derived from human ATRIP, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Bovine,Sheep,Rabbit
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2837901
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF5417-BP
Des# Blocking Peptide : ATRIP Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : Ataxia telangiectasia and Rad3 related antibody; Ataxia telangiectasia and Rad3-related protein antibody; ATR antibody; ATR_HUMAN antibody; FCTCS antibody; FRAP Related Protein 1 antibody; FRAP-related protein 1 antibody; FRP1 antibody; MEC1 antibody; MEC1 mitosis entry checkpoint 1 homolog antibody; Protein kinase ATR antibody; RAC3 antibody; Rad3 related protein antibody; SCKL antibody; SCKL1 antibody; Serine/threonine protein kinase ATR antibody; Serine/threonine-protein kinase ATR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13535
Immunogen : Recombinant Human Serine/threonine-protein kinase ATR protein (2405-2644AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), µLtraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates BRCA1 CHEK1 MCM2, RAD17, RPA2, SMC1 and p53/TP53, which collectively inhibit DNA replication and mitosis and promote DNA repair, recombination and apoptosis. Phosphorylates \\\'Ser-139\\\' of histone variant H2AX/H2AFX at sites of DNA damage, thereby reg µLating DNA damage response mechanism. Required for FANCD2 ubiquitination. Critical for maintenance of fragile site stability and efficient reg µLation of centrosome duplication.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATR
Research Areas : Epigenetics and Nuclear Signaling; Cancer